7/14/2023 0 Comments Plasminogen activatorThe researchers found that the treatment substantially reduced tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator activity. The researchers gave intracerebroventricular injections of plasminogen activator inhibitor-1 to rat pups following carotid ligation and 90 minutes of hypoxia. 3 (HealthDay News) - Inhibiting tissue-type plasminogen activators could be useful in preventing brain injury in infants with oxygen or blood-flow deprivation, according to research published July 8 in the Journal of Neuroscience.ĭianer Yang, Ph.D., of the Cincinnati Children's Hospital Medical Center, and colleagues analyzed data from a rat model of cerebral hypoxia-ischemia.
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